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CYM-5541

Chemical Structure : CYM-5541

CAS No.: 945128-26-7

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CYM-5541 (ML249, CYM5541, CYM 5541)

Catalog No.: PC-42379Not For Human Use, Lab Use Only.

CYM-5541 (ML249) is a potent, selective, allosteric and full agonist of S1P3 receptor with EC50 of 72-132 nM.

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10 mg $98 In stock
25 mg $168 In stock
50 mg $268 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CYM-5541 (ML249) is a potent, selective, allosteric and full agonist of S1P3 receptor with EC50 of 72-132 nM.
CYM-5541 exhibits exquisite selectivity over other S1P receptor subtypes in vitro (EC50>10 uM), also shows no significant activities against panel of 55 GPCRs, ion channels, and transporters.

Physicochemical Properties

M.Wt 316.43782
Formula C19H28N2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

DMSO: ≥ 39 mg/mL
Chemical Name/SMILES

3-Isoxazolecarboxamide, N,N-dicyclohexyl-5-cyclopropyl-

References

1. Jo E, et al. ACS Chem Biol. 2012 Dec 21;7(12):1975-83.

2. St-Cyr Giguère F, et al. Brain Res. 2017 Mar 1;1658:51-59.

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