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CYM51010

Chemical Structure : CYM51010

CAS No.: 1069498-96-9

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CYM51010 (CID23723457, OPRM1-OPRD1 agonist ML335)

Catalog No.: PC-62146Not For Human Use, Lab Use Only.

CYM51010 (ML335) is an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization with EC50 of 403 nM.

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10 mg $148 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CYM51010 (ML335) is an agonist probe for opioid receptor mu 1 (OPRM1)-opioid receptor delta 1 (OPRD1) heterodimerization with EC50 of 403 nM.
ML335 displays 37, 2.7, and >99-fold selectivity over OPRM1, OPRD1, and HTR5A, respectively.

Physicochemical Properties

M.Wt 408.542
Formula C25H32N2O3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
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Solubility

10 mM in DMSO
Chemical Name/SMILES

1-[[4-(acetylamino)phenyl]methyl]-4-(2-phenylethyl)-4-piperidinecarboxylic acid, ethyl ester

References

1. Pinello C, et al. Probe Reports from the NIH Molecular Libraries Program [Internet].

2. Lolicato M, et al. Nature. 2017 Jul 10. doi: 10.1038/nature22988.

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