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CZS-089

Chemical Structure : CZS-089

CAS No.:

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CZS-089 (CZS089)

Catalog No.: PC-25891Not For Human Use, Lab Use Only.

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

CZS-089 is a potent, selective PLK4 inhibitor with IC50 of 26 nM.

Physicochemical Properties

M.Wt 503.51
Formula C24H18FN7O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1-(3-fluoro-5-(5-(3-(methylsulfonyl)phenyl)-1H-pyrazolo[3,4-b]pyridin-3-yl)phenyl)-3-(pyrimidin-5-yl)urea

References

1. Yin Sun, et al. J Med Chem. 2023 Feb 23;66(4):2396-2421.

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