Chemical Structure : CZV1-1
CAS No.:
CZV1-1
Catalog No.: PC-22896Not For Human Use, Lab Use Only.
CZV1-1 is a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope., purified anti-CZV1-1 IgG neutralizes infection of ZIKV in cell cultures with potencies comparable to highly specific ZIKV-neutralizing mAbs.
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Purity & Documentation Purity:
>98% (HPLC)
Biological Activity
CZV1-1 is a nonbiological small-molecular mimic of a Zika virus conformational neutralizing epitope., purified anti-CZV1-1 IgG neutralizes infection of ZIKV in cell cultures with potencies comparable to highly specific ZIKV-neutralizing mAbs.
CZV1-1 mimics a nonlinear, neutralizing conformational epitope in the domain III of the ZIKV envelope.
Physicochemical Properties
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M.Wt
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1152.32
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Formula
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C62H73N9O13
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Appearance
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Solid
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CAS No.
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Storage
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- Solide Powder
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-20°C 12 Months; 4°C 6 Months
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- In Solvent
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-80°C 6 Months; -20°C 6 Months
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Shipping
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Solubility
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10 mM in DMSO
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Chemical Name/SMILES
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(S)-3-((1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)-N-(4-(2-(3-((1,4-dioxa-8-azaspiro[4.5]decan-8-yl)methyl)benzamido)-13-(2-amino-2-oxoethyl)-4-(benzo[d][1,3]dioxol-5-ylmethyl)-3,12-dioxo-7,10-dioxa-4,13-diazahexadec-15-yn-1-yl)phenyl)-N-((1H-imidazol-2-yl)methyl)benzamide
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References
1. Castanha PMS, et al. Proc Natl Acad Sci U S A. 2024 May 21;121(21):e2312755121.
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