Cabazitaxel | Microtubule inhibitor | Probechem Biochemicals

Chemical Structure : Cabazitaxel

CAS No.: 183133-96-2

Cabazitaxel (XRP6258, XRP 6258)

Catalog No.: PC-61247Not For Human Use, Lab Use Only.

Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer.

Packing	Price	Stock
50 mg	$78	In stock
100 mg	$118	In stock
500 mg	$348	In stock
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Biological Activity

Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer.
Cabazitaxel possesses a favorable pharmacokinetic and safety profile, and a decreased propensity for P-glycoprotein (Pgp)-mediated drug resistance.

Physicochemical Properties

M.Wt	835.932
Formula	C45H57NO14
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	Benzenepropanoic acid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-y

References

1. Villanueva C, et al. Drugs. 2011 Jul 9;71(10):1251-8.

2. Madan RA, et al. Clin Cancer Res. 2011 Jun 15;17(12):3892-902.

3. Bouchet BP, et al. Drugs Today (Barc). 2010 Oct;46(10):735-42.

Cabazitaxel (XRP6258, XRP 6258)

Biological Activity

Physicochemical Properties

References

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