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Chemical Structure : Cabazitaxel
CAS No.: 183133-96-2
Catalog No.: PC-61247Not For Human Use, Lab Use Only.
Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $78 | In stock | |
| 100 mg | $118 | In stock | |
| 500 mg | $348 | In stock | |
| 1 g | Get quote |
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Cabazitaxel (XRP6258) is a semi-synthetic taxane and microtubule inhibitor for the treatment of hormone-refractory prostate cancer.
Cabazitaxel possesses a favorable pharmacokinetic and safety profile, and a decreased propensity for P-glycoprotein (Pgp)-mediated drug resistance.
| M.Wt | 835.932 | |
| Formula | C45H57NO14 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzenepropanoic acid, b-[[(1,1-dimethylethoxy)carbonyl]amino]-a-hydroxy-, 12b-(acetyloxy)-12-(benzoyloxy)-2a,3,4,4a,5,6,9,10,11,12,12a,12b-dodecahydro-11-hydroxy-4,6-dimethoxy-4a,8,13,13-tetramethyl-5-oxo-7,11-methano-1H-cyclodeca[3,4]benz[1,2-b]oxet-9-y |
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1. Villanueva C, et al. Drugs. 2011 Jul 9;71(10):1251-8.
2. Madan RA, et al. Clin Cancer Res. 2011 Jun 15;17(12):3892-902.
3. Bouchet BP, et al. Drugs Today (Barc). 2010 Oct;46(10):735-42.
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