Chemical Structure : Cadazolid
CAS No.: 1025097-10-2
Catalog No.: PC-22350Not For Human Use, Lab Use Only.
Cadazolid (ACT-179811) is a first-in-class quinoxolidinone antibiotic and a potent inhibitor of C. difficile protein synthesis with IC50 of 0.38 uM in in vitro transcription/translation assay, MIC of <0.03 ug/mL against Clostridioides difficile ATCC 700057.
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Cadazolid (ACT-179811) is a first-in-class quinoxolidinone antibiotic and a potent inhibitor of C. difficile protein synthesis with IC50 of 0.38 uM in in vitro transcription/translation assay, MIC of <0.03 ug/mL against Clostridioides difficile ATCC 700057.
M.Wt | 585.56 | |
Formula | C29H29F2N3O8 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
(R)-1-cyclopropyl-6-fluoro-7-(4-((2-fluoro-4-(5-(hydroxymethyl)-2-oxooxazolidin-3-yl)phenoxy)methyl)-4-hydroxypiperidin-1-yl)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid |
1. Rueedi G, et al. J Med Chem. 2024 May 16. doi: 10.1021/acs.jmedchem.4c00558.
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