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Calpeptin

Chemical Structure : Calpeptin

CAS No.: 117591-20-5

Calpeptin

Catalog No.: PC-73381Not For Human Use, Lab Use Only.

Calpeptin is a potent, cell penetrating calpain inhibitor with ID50 of 40 nM for Calpain I in human platelets, also inhibits cathepsin K and is a potent and specific inhibitor of SARS-CoV-2 entry and some variants.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Calpeptin is a potent, cell penetrating calpain inhibitor with ID50 of 40 nM for Calpain I in human platelets, also inhibits cathepsin K and is a potent and specific inhibitor of SARS-CoV-2 entry and some variants.

Physicochemical Properties

M.Wt 362.46
Formula C20H30N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Benzyl ((S)-4-methyl-1-oxo-1-(((S)-1-oxohexan-2-yl)amino)pentan-2-yl)carbamate

References

1. Tsujinaka T, et al. Biochem Biophys Res Commun. 1988 Jun 30;153(3):1201-8.

2. Catalano JG, et al. Bioorg Med Chem Lett. 2004 Feb 9;14(3):719-22.

3. Sonia Mediouni, et al. SLAS Discov. 2022 Jan;27(1):8-19.

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