Camptothecin | Topo I inhibitor | Probechem Biochemicals

Chemical Structure : Camptothecin

CAS No.: 7689-03-4

Camptothecin (Campathecin, (S)-(+)-Camptothecin, CPT)

Catalog No.: PC-27848Not For Human Use, Lab Use Only.

Camptothecin (CPT) is a kind of alkaloid and potent specific DNA topoisomerase I (Topo I) inhibitor with IC50 of 679 nM, exhibits broad antineoplastic activity against multiple cancers.

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Biological Activity

Camptothecin (CPT) is a kind of alkaloid and potent specific DNA topoisomerase I (Topo I) inhibitor with IC50 of 679 nM, exhibits broad antineoplastic activity against multiple cancers.

Physicochemical Properties

M.Wt	348.36
Formula	C20H16N2O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	(S)-4-Ethyl-4-hydroxy-1H-pyrano[3',4':6,7]indolizino[1,2-b]quinoline-3,14(4H,12H)-dione

References

1. Luzzio MJ, et al. J Med Chem. 1995 Feb 3;38(3):395-401.

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Camptothecin (Campathecin, (S)-(+)-Camptothecin, CPT)

Biological Activity

Physicochemical Properties

References

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