Candoxatril |CAS:123122-55-4 Probechem Biochemicals

Chemical Structure : Candoxatril

Catalog No.: PC-60712Not For Human Use, Lab Use Only.

The orally active prodrug of candoxatrilat (UK-73967), potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

The orally active prodrug of candoxatrilat (UK-73967), potent neutral endopeptidase EC 3.4.24.11 (atriopeptidase) inhibitor.

Heart Failure

Discontinued

M.Wt	515.638
Formula	C29H41NO7
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-{[(1-{3-(2,3-dihydro-1H-inden-5-yloxy)-2-[(2-methoxyethoxy)methyl]-3-oxopropyl}cyclopentyl)carbonyl]amino}cyclohexanecarboxylic acid

1. Danilewicz JC, et al. Biochem Biophys Res Commun. 1989 Oct 16;164(1):58-65.

2. Shepperson NB, et al. Br J Pharmacol. 1989 Dec;98 Suppl:822P.

3. Jardine AG, et al. Am J Hypertens. 1990 Sep;3(9):661-7.

4. Northridge DB, et al. Lancet. 1989 Sep 9;2(8663):591-3.