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Caplacizumab

Chemical Structure : Caplacizumab

CAS No.:

Caplacizumab (Anti-human vWF mAb, human Fc; ALX-0081)

Catalog No.: PC-Ab1068Not For Human Use, Lab Use Only.

Caplacizumab (ALX0081) is a humanized single variable domain immunoglobulin (nanobody) against the von Willebrand factor (VWF). by targetting the A1 domain of the ultra-large von Willebrand factor which in order inhibits the interaction with the glycoprotein Ib-IX-V receptor in the platelets. Caplacizumab has used to treat acquired thrombotic thrombocytopenic purpura (aTTP)..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Caplacizumab (ALX0081) is a humanized single variable domain immunoglobulin (nanobody) against the von Willebrand factor (VWF). by targetting the A1 domain of the ultra-large von Willebrand factor which in order inhibits the interaction with the glycoprotein Ib-IX-V receptor in the platelets. Caplacizumab has used to treat acquired thrombotic thrombocytopenic purpura (aTTP).

Physicochemical Properties

M.Wt
Formula Human Fc
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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