Capstafin |CAS:1818390-52-1 Probechem Biochemicals

Chemical Structure : Capstafin

Capstafin

Catalog No.: PC-61629Not For Human Use, Lab Use Only.

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.

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Biological Activity

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.
Capstafin displays 35-fold selectivity over the highly homologous STAT5a, >20-fold selectivity over STAT6, and >45-fold selectivity over STAT4.

Physicochemical Properties

M.Wt	453.365
Formula	C17H29NO9P2
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4-((8-methylnonanamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

References

1. Elumalai N, et al. ACS Chem Biol. 2015 Dec 18;10(12):2884-90.

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Capstafin

Biological Activity

Physicochemical Properties

References

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