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Capstafin

Chemical Structure : Capstafin

CAS No.: 1818390-52-1

Capstafin

Catalog No.: PC-61629Not For Human Use, Lab Use Only.

Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Capstafin is a phosphorylation of capsaicinoid derivative that acts as a highly potent, selective inhibitor of STAT5b with Ki of 0.34 uM.
    Capstafin displays 35-fold selectivity over the highly homologous STAT5a, >20-fold selectivity over STAT6, and >45-fold selectivity over STAT4.

    Physicochemical Properties

    M.Wt 453.365
    Formula C17H29NO9P2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    4-((8-methylnonanamido)methyl)-1,2-phenylene bis(dihydrogen phosphate)

    References

    1. Elumalai N, et al. ACS Chem Biol. 2015 Dec 18;10(12):2884-90.

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