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Captopril

Chemical Structure : Captopril

CAS No.: 62571-86-2

Captopril (SQ 14225)

Catalog No.: PC-25271Not For Human Use, Lab Use Only.

Captopril (SQ 14225) is antihypertensive agent that acts as a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC50 of 25 nM, is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with IC50 of 7.9 uM.

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50 mg $28 In stock
100 mg $38 In stock
500 mg $58 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Captopril (SQ 14225) is antihypertensive agent that acts as a thiol-containing competitive, orally active angiotensin-converting enzyme (ACE) inhibitor with IC50 of 25 nM, is also a New Delhi metallo-β-lactamase-1 (NDM-1) inhibitor with IC50 of 7.9 uM.

Physicochemical Properties

M.Wt 217.28
Formula C9H15NO3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-1-((S)-3-mercapto-2-methylpropanoyl)pyrrolidine-2-carboxylic acid

References

1. Afrin S, et al. J Agric Food Chem. 2016;64(11):2263-2268.

2. Li N, et al. Bioorg Med Chem Lett. 2014;24(1):386-389.

3. Tzakos, A.G., et al. Bioorg Med Chem Lett, 2006. 16(19): p. 5084-7.

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