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Carbenoxolone disodium

Chemical Structure : Carbenoxolone disodium

CAS No.: 7421-40-1

Carbenoxolone disodium (YP 003 disodium)

Catalog No.: PC-60343Not For Human Use, Lab Use Only.

Carbenoxolone disodium is a glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Carbenoxolone disodium is a glycyrrhetinic acid derivative that inhibits 11β-hydroxysteroid dehydrogenase (11β-HSD), a gap junction blocker and mineralocorticoid agonist.

Physicochemical Properties

M.Wt 614.731
Formula C34H48Na2O7
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(3β,20β)-3-(3-Carboxy-1-oxopropoxy)-11-oxoolean-12-en-29-oic acid disodium

References

1. Sagar GD, et al. J Cell Biochem. 2006 Aug 15;98(6):1543-51.

2. Hanukoglu A, et al. J Steroid Biochem Mol Biol. 1997 Jan;60(1-2):105-12.

3. Lindsay RS, et al. Hypertension. 1996 Jun;27(6):1200-4.

4. Ross FM, et al. Neuroscience. 2000;100(4):789-96.

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