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Cardionogen 1

Chemical Structure : Cardionogen 1

CAS No.: 577696-37-8

Cardionogen 1 (CDNG1/vuc230, Cardionogen-1)

Catalog No.: PC-62447Not For Human Use, Lab Use Only.

Cardionogen 1 (CDNG1/vuc230, Cardionogen-1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cardionogen 1 (CDNG1/vuc230, Cardionogen-1) is a small molecule that promotes cardiomyocyte generation by modulating Wnt signaling.
Cardionogen 1 inhibits Wnt/β-catenin-dependent transcription in murine ES cells and zebrafish embryos.
Cardionogen 1 rescues Wnt8-induced cardiomyocyte deficiency and heart-specific phenotypes during development.

Physicochemical Properties

M.Wt 274.342
Formula C13H14N4OS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Cyclohexyl-3-furan-2-yl-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazole

References

1. Ni TT, et al. Chem Biol. 2011 Dec 23;18(12):1658-68.

2. Yan C, et al. Sci Rep. 2017 Apr 5;7:45796.

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