Carnosic acid |CAS:3650-09-7 Probechem Biochemicals

Chemical Structure : Carnosic acid

CAS No.: 3650-09-7

Carnosic acid (Carnosate)

Catalog No.: PC-61323Not For Human Use, Lab Use Only.

Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM.

Packing	Price	Stock
50 mg	$148	In stock
100 mg	$228	In stock
200 mg	$368	In stock
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Biological Activity

Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM.
Carnosic acid inhibits β-catenin-dependent transcription, and destabilizes oncogenic β-catenin in colon cancer cells.
Carnosic acid reduces the expression of Sox2 and the number of SOX2+ cells in MB sphere cultures.

Physicochemical Properties

M.Wt	332.4
Formula	C20H28O4
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)-

References

1. Rodriguez-Blanco J, et al. Oncogene. 2017 Jul 17. doi: 10.1038/onc.2017.232.

2. de la Roche M, et al. Nat Commun. 2012 Feb 21;3:680.

3. de la Roche M, et al. Cancer Res. 2014 Mar 1;74(5):1495-505.

Carnosic acid (Carnosate)

Biological Activity

Physicochemical Properties

References

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