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Chemical Structure : Carnosic acid
CAS No.: 3650-09-7
Catalog No.: PC-61323Not For Human Use, Lab Use Only.
Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 50 mg | $148 | In stock | |
| 100 mg | $228 | In stock | |
| 200 mg | $368 | In stock | |
| 1 g | Get quote |
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Carnosic acid (Carnosate) is a naturally occurring phenolic compound with antioxidant, anti-inflammatory and antimicrobial properties, inhibits the BCL9/β-catenin interaction with Ki of 3.3 uM.
Carnosic acid inhibits β-catenin-dependent transcription, and destabilizes oncogenic β-catenin in colon cancer cells.
Carnosic acid reduces the expression of Sox2 and the number of SOX2+ cells in MB sphere cultures.
| M.Wt | 332.4 | |
| Formula | C20H28O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
4a(2H)-Phenanthrenecarboxylic acid, 1,3,4,9,10,10a-hexahydro-5,6-dihydroxy-1,1-dimethyl-7-(1-methylethyl)-, (4aR-trans)- |
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1. Rodriguez-Blanco J, et al. Oncogene. 2017 Jul 17. doi: 10.1038/onc.2017.232.
2. de la Roche M, et al. Nat Commun. 2012 Feb 21;3:680.
3. de la Roche M, et al. Cancer Res. 2014 Mar 1;74(5):1495-505.
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