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Caspofungin diacetate

Chemical Structure : Caspofungin diacetate

CAS No.: 179463-17-3

Caspofungin diacetate (L-743872, MK-0991)

Catalog No.: PC-45132Not For Human Use, Lab Use Only.

Caspofungin diacetate (L-743872, MK-0991) is a lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Caspofungin diacetate (L-743872, MK-0991) is a lipopeptide antifungal agent that works by inhibiting the enzyme 1,3-beta-glucan synthase and thereby disturbing the integrity of the fungal cell wall.

Physicochemical Properties

M.Wt 1213.417
Formula C56H96N10O19
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

H2O: ≥ 100 mg/mL

Chemical Name/SMILES

Pneumocandin B0, 1-[(4R,5S)-5-[(2-aminoethyl)amino]-N2-[(10R,12S)-10,12-dimethyl-1-oxotetradecyl]-4-hydroxy-L-ornithine]-5-[(3R)-3-hydroxy-L-ornithine]-, acetate (1:2)

References

1. Campbell JA, et al. Biochem J. 1997 Sep 15;326 ( Pt 3):929-39.

2. Mio T, et al. J Bacteriol. 1997 Jul;179(13):4096-105.

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