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CatL inhibitor 1

Chemical Structure : CatL inhibitor 1

CAS No.: 225120-65-0

CatL inhibitor 1 (Cathepsin inhibitor 25)

Catalog No.: PC-23817Not For Human Use, Lab Use Only.

CatL inhibitor 1 is a potent, selective inhibitor of cathepsin L (CatL) with pIC50 of 7.9, >10-fold selective over CatL2 and >100 fold over CatS/K/B.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

CatL inhibitor 1 is a potent, selective inhibitor of cathepsin L (CatL) with pIC50 of 7.9, >10-fold selective over CatL2 and >100 fold over CatS/K/B.

Physicochemical Properties

M.Wt 401.90
Formula C20H24ClN5O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(S)-3-(tert-Butyl)-N-(3-(3-chlorophenyl)-1-((cyanomethyl)amino)-1-oxopropan-2-yl)-1-methyl-1H-pyrazole-5-carboxamide

References

1. Asaad N, et, al. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4280-3.

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