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Chemical Structure : Cathepsin G inhibitor KPA
Catalog No.: PC-22250Not For Human Use, Lab Use Only.
Cathepsin G inhibitor KPA is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (CatG) with IC50 of 53 nM.
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Cathepsin G inhibitor KPA is a potent, selective, reversible, competitive, non-peptide inhibitor of cathepsin G (CatG) with IC50 of 53 nM.
Cathepsin G inhibitor KPA weakly inhibits chymotrypsin (Ki = 1.5 ± 0.2 μM), and poorly inhibits (<50% inhibition at 100 μM) thrombin, factor Xa, factor IXa, plasmin, trypsin, tryptase, proteinase 3, and human leukocyte elastase.
| M.Wt | 620.64 | |
| Formula | C36H33N2O6P | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Michael N Greco, et al. J Am Chem Soc. 2002 Apr 17;124(15):3810-1.
2. Son ED, et al. Dermatology. 2012;224(4):352-60.
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