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Chemical Structure : Cavosonstat
Catalog No.: PC-60035Not For Human Use, Lab Use Only.
Cavosonstat (N91115, N-91115) is a potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator.
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Cavosonstat (N91115, N-91115) is a potent, orally bioavailable inhibitor of S-nitrosoglutathione reductase (GSNOR) and CFTR modulator; promotes CFTR maturation and plasma membrane stability, with a mechanism of action complementary to CFTR correctors and potentiators; significantly increases cell surface expression of F508del-CFTR in vitro combined with CFTR correctors.
Cystic Fibrosis
Phase 2 Discontinued
| M.Wt | 299.71 | |
| Formula | C16H10ClNO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Donaldson SH, et al. J Cyst Fibros. 2017 May;16(3):371-379.
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