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Chemical Structure : Cecropin B
CAS No.: 80451-05-4
Catalog No.: PC-47495Not For Human Use, Lab Use Only.
Cecropin B is an antimicrobial peptide with MICs (0.5 to 16 ug/ml) against Gram negative strain, also inhibit the expression of CYP3A29.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $118 | In stock | |
| 5 mg | $288 | In stock | |
| 10 mg | $458 | In stock | |
| 25 mg | Get quote |
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Cecropin B is an antimicrobial peptide with MICs (0.5 to 16 ug/ml) against Gram negative strain, also inhibit the expression of CYP3A29.
Cecropin B induces NF-κB activation playing a pivotal role in the suppression of CYP3A29 through disrupting the association of the PXR/retinoid X receptor alpha (RXR-α) complex with DNA sequences.
Cecropin B activates pig liver cells by interacting with TLRs 2 and 4, which modulated NF-κB-mediated signaling pathways
| M.Wt | 3834.67 | |
| Formula | C176H302N52O41S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 10 mM (38.3 mg/mL) |
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| Chemical Name/SMILES |
L-Leucinamide, L-lysyl-L-tryptophyl-L-lysyl-L-valyl-L-phenylalanyl-L-lysyl-L-lysyl-L-isoleucyl-L-α-glutamyl-L-lysyl-L-methionylglycyl-L-arginyl-L-asparaginyl-L-isoleucyl-L-arginyl-L-asparaginylglycyl-L-isoleucyl-L-valyl-L-lysyl-L-alanylglycyl-L-prolyl-L-a |
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1. Hu H, et al. Mol Cells. 2013 Feb;35(2):106-14.
2. Zhou X, et al. Sci Rep. 2016 Jun 14;6:27876.
3. Chen F, et al. J Mol Microbiol Biotechnol. 2015;25(4):284-91.
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