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Cenerimod

Chemical Structure : Cenerimod

CAS No.: 1262414-04-9

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Cenerimod (ACT-334441, ACT334441)

Catalog No.: PC-45386Not For Human Use, Lab Use Only.

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM.

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5 mg $78 In stock
10 mg $118 In stock
25 mg $198 In stock
50 mg $348 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cenerimod (ACT-334441) is a potent and orally available S1P1 receptor agonist with EC50 of 2.7 nM.
Cenerimod (ACT-334441) shows a powerful and long-lasting immunomodulating effect by reducing the number of circulating and infiltrating T- and B-lymphocytes, without affecting their maturation, memory, or expansion.

Physicochemical Properties

M.Wt 453.5307
Formula C25H31N3O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

1,2-Propanediol, 3-[4-[5-(2-cyclopentyl-6-methoxy-4-pyridinyl)-1,2,4-oxadiazol-3-yl]-2-ethyl-6-methylphenoxy]-, (2S)-

References

1. Piali L, et, al. Pharmacol Res Perspect. 2017 Dec;5(6):e00370.

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