Cevimeline |CAS:107233-08-9 Probechem Biochemicals

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Chemical Structure : Cevimeline

CAS No.: 107233-08-9

Cevimeline (AF-102B;FKS-508)

Catalog No.: PC-45938Not For Human Use, Lab Use Only.

A potent M1-selective muscarinic agonist.

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10 mg	$88	In stock
50 mg	$360	In stock

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

A potent M1-selective muscarinic agonist; decreases the K+-evoked [3H]ACh release from hippocampal synaptosomes and increases the K+-evoked [3H]DA release from striatal synaptosomes; attenuates cognitive dysfunctions in AF64A-treated rats with low toxicity.

Other Indication

Approved

Physicochemical Properties

M.Wt	199.3131
Formula	C10H17NOS
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel-

References

1. Ono S, et al. Eur J Pharmacol. 1988 Oct 11;155(1-2):77-84.

2. Fisher A, et al. Neurosci Lett. 1989 Jul 31;102(2-3):325-31.

3. Nakahara N, et al. Jpn J Pharmacol. 1989 Dec;51(4):539-47.

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Cevimeline (AF-102B;FKS-508)

Biological Activity

Physicochemical Properties

References

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