Chemical Structure : Cevimeline
CAS No.: 107233-08-9
Catalog No.: PC-45938Not For Human Use, Lab Use Only.
A potent M1-selective muscarinic agonist.
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A potent M1-selective muscarinic agonist; decreases the K+-evoked [3H]ACh release from hippocampal synaptosomes and increases the K+-evoked [3H]DA release from striatal synaptosomes; attenuates cognitive dysfunctions in AF64A-treated rats with low toxicity.
Other Indication
Approved
M.Wt | 199.3131 | |
Formula | C10H17NOS | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
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Chemical Name/SMILES |
Spiro[1-azabicyclo[2.2.2]octane-3,5'-[1,3]oxathiolane], 2'-methyl-, (2'R,3R)-rel- |
1. Ono S, et al. Eur J Pharmacol. 1988 Oct 11;155(1-2):77-84.
2. Fisher A, et al. Neurosci Lett. 1989 Jul 31;102(2-3):325-31.
3. Nakahara N, et al. Jpn J Pharmacol. 1989 Dec;51(4):539-47.
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