Chemical Structure : Charybdotoxin
CAS No.:
95751-30-7
Charybdotoxin
(ChTX;CTX)
Catalog No. : PC-60655Not For Human Use, Lab Use Only.
Charybdotoxin (ChTX) selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK).
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6065501
Biological Activity
Charybdotoxin (ChTX) selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa , KCa1.1, MaxiK).
Physicochemical Properties
M.Wt
4295.89
Formula
C176H277N57O55S7
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
H2O: 1.0 mg/ml
Chemical Name/SMILES
XFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (Modifications: X-1 = Glp, Disulfide bridge between 7 - 28, 13 - 33,17 - 35, Ser-37 = C-terminal OH)
References
1. Suarez-Kurtz G, et al. J Pharmacol Exp Ther
2. Smith C, et al. J Biol Chem
3. Miller C, et al. Nature
4. Chang CC, et al. Br J Pharmacol
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