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Chemical Structure : Charybdotoxin
CAS No.: 95751-30-7
Catalog No.: PC-60655Not For Human Use, Lab Use Only.
Charybdotoxin (ChTX) selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 100 ug | $188 | In stock | |
| 500 ug | $298 | In stock | |
| 1 mg | $478 | In stock | |
| 5 mg | Get quote |
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Charybdotoxin (ChTX) selective, potent peptidyl blocker of the big conductance Ca2+-activated K+ channel (BKCa, KCa1.1, MaxiK).
Charybdotoxin produces a concentration-dependent increase in contractility at 10-100 nM in guinea pig smooth muscle tissues.
| M.Wt | 4295.89 | |
| Formula | C176H277N57O55S7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 1.0 mg/ml |
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| Chemical Name/SMILES |
XFTNVSCTTSKECWSVCQRLHNTSRGKCMNKKCRCYS (Modifications: X-1 = Glp, Disulfide bridge between 7 - 28, 13 - 33,17 - 35, Ser-37 = C-terminal OH) |
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1. Suarez-Kurtz G, et al. J Pharmacol Exp Ther. 1991 Oct;259(1):439-43.
2. Smith C, et al. J Biol Chem. 1986 Nov 5;261(31):14607-13.
3. Miller C, et al. Nature. 1985 Jan 24-30;313(6000):316-8.
4. Chang CC, et al. Br J Pharmacol. 1983 Jul;79(3):673-80.
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