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Ciclopirox

Chemical Structure : Ciclopirox

CAS No.: 29342-05-0

Ciclopirox (HOE296b)

Catalog No.: PC-27041Not For Human Use, Lab Use Only.

Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent, shows broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic, also inhibits cholesterol 25-hydroxylase (CH25H).

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Biological Activity

Ciclopirox (HOE296b) is a synthetic and orally active antifungal agent, shows broad spectrum of activity and inhibits dermatophytes, yeasts, molds, and many Gram-positive and Gram-negative species pathogenic, also inhibits cholesterol 25-hydroxylase (CH25H).

Physicochemical Properties

M.Wt 207.27
Formula C12H17NO2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

6-Cyclohexyl-1-hydroxy-4-methylpyridin-2(1H)-one

References

1. Niewerth, M. et al. Antimicrob Agents Chemother, 2003. 47(6): p. 1805-17.

2. Zhou H, et al. Int J Cancer. 2010 Nov 15;127(10):2467-77.

3. Rahman A, et al. ACS Chem Biol. 2026 Jun 12. doi: 10.1021/acschembio.6c00385.

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