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Cisplatin

Chemical Structure : Cisplatin

CAS No.: 15663-27-1

Cisplatin (CDDP, cis-Diaminodichloroplatinum)

Catalog No.: PC-45216Not For Human Use, Lab Use Only.

Cisplatin is a chemotherapy agent that interferes with DNA replication and kills cancer cells.

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Biological Activity

Cisplatin is a chemotherapy agent that interferes with DNA replication and kills cancer cells.
Cisplatin induces growth arrest and/or apoptosis in most cancer cell types.
Cisplatin is an alkylating agent for treatment of a number of cancers.

Physicochemical Properties

M.Wt 300.051
Formula Cl2H6N2Pt
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 31 mg/mL (DMSO can inactivate Cisplatin's activity; please see the reference [5]).

Chemical Name/SMILES

Platinum, diamminedichloro-, (SP-4-2)-

References

1. Wang X, et al. J Biol Chem. 2000 Dec 15;275(50):39435-43.

2. Cummings BS, et al. J Pharmacol Exp Ther. 2002 Jul;302(1):8-17.

3. Hall MD, et al. Cancer Res. 2014 Jul 15;74(14):3913-22.

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