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Citronellol

Chemical Structure : Citronellol

CAS No.: 106-22-9

Citronellol ((±)-Citronellol)

Catalog No.: PC-23024Not For Human Use, Lab Use Only.

Citronellol is an orally active inducer of apoptosis and RIPK1 agonist.

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Biological Activity

Citronellol is an orally active inducer of apoptosis and RIPK1 agonist.
Citronellol prevents oxidative stress, mitochondrial dysfunction, and apoptosis in the SH-SY5Y cell Parkinson's disease model induced by 6-OHDA by regulating the ROS-NO, MAPK/ERK, and PI3K/Akt signaling pathways.
Citronellol reduces the levels of LC-3 and p62 to regulate the autophagy pathway, inhibits oxidative stress and neuroinflammation, and thus have neuroprotective effects on Parkinson's rats.
Citronellol exhibits anti-fungal activity against Trichophyton rubrum by inhibiting ergosterol synthesis.

Physicochemical Properties

M.Wt 156.27
Formula C10H20O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3,7-Dimethyloct-6-en-1-ol

References

1. Gong Q, et al. Cell Commun Signal. 2024 Sep 2;22(1):427.

2. Munir S, et al. Biomedicines. 2023 Oct 18;11(10):2820.

3. Shao J, et al. Neurotox Res. 2022 Dec;40(6):2221-2237

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