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Chemical Structure : Clazakizumab
CAS No.:
Catalog No.: PC-Ab1084Not For Human Use, Lab Use Only.
Clazakizumab (ALD518, BMS 945429) a humanized anti–IL-6 mAb, targets human IL-6 with an affinity of 4 pM, binds circulating IL-6 cytokine rather than the IL-6 receptor 10, 11, blocking both classic signaling and trans-signaling. significantly improves disease activity in rheumatoid arthritis (RA). It has also been evaluated for the treatment of non-small cell lung cancer (NSCLC) and patients with head and neck cancer..
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 1 mg | $358 | In stock | |
| 5 mg | $758 | In stock | |
| 10 mg | $1280 | In stock | |
| 100 mg | Get quote |
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Clazakizumab (ALD518, BMS 945429) a humanized anti–IL-6 mAb, targets human IL-6 with an affinity of 4 pM, binds circulating IL-6 cytokine rather than the IL-6 receptor 10, 11, blocking both classic signaling and trans-signaling. significantly improves disease activity in rheumatoid arthritis (RA). It has also been evaluated for the treatment of non-small cell lung cancer (NSCLC) and patients with head and neck cancer.
| M.Wt | ||
| Formula | Human IgG1-Kappa | |
| Appearance | Solid | |
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| Solubility |
PBS, pH 7.0 Contains no stabilizers or preservatives |
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