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Codrituzumab

Chemical Structure : Codrituzumab

CAS No.:

Codrituzumab (Anti-human GPC3 mAb, human IgG1-Kappa; RG 7686; RO 5137382)

Catalog No.: PC-Ab1037Not For Human Use, Lab Use Only.

Codrituzumab is a humanized monoclonal antibody targeted at glypican-3 (GPC3), which is a member of the glypican family. Codrituzumab binds to glypican-3 (GPC3). Glypican-3 (GPC3) is highly expressed in hepatocellular carcinoma (HCC). Codrituzumab triggers FcγRIIIa-mediated (CD16-mediated) antibody-dependent cell cytotoxicity (ADCC) and/or antibody-dependent cell phagocytosis..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Codrituzumab is a humanized monoclonal antibody targeted at glypican-3 (GPC3), which is a member of the glypican family. Codrituzumab binds to glypican-3 (GPC3). Glypican-3 (GPC3) is highly expressed in hepatocellular carcinoma (HCC). Codrituzumab triggers FcγRIIIa-mediated (CD16-mediated) antibody-dependent cell cytotoxicity (ADCC) and/or antibody-dependent cell phagocytosis.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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