Chemical Structure : Compound 1105486
CAS No.: 683794-45-8
Catalog No.: PC-25464Not For Human Use, Lab Use Only.
Compound 1105486 is a selective small molecule inhibitor of β-1,4-galactosyltransferase 1 (B4GALT1), suppresses PANC-1 cell proliferation with an IC50 of 19.8 uM, exhibiting no significant cytotoxicity toward hTERT-HPNE normal pancreatic ductal epithelial cells up to 80 uM
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Compound 1105486 is a selective small molecule inhibitor of β-1,4-galactosyltransferase 1 (B4GALT1), suppresses PANC-1 cell proliferation with an IC50 of 19.8 uM, exhibiting no significant cytotoxicity toward hTERT-HPNE normal pancreatic ductal epithelial cells up to 80 uM.
| M.Wt | 471.50 | |
| Formula | C23H22FN3O5S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
2-((3-cyano-6-oxo-4-(3,4,5-trimethoxyphenyl)-3,4,5,6-tetrahydropyridin-2-yl)thio)-N-(4-fluorophenyl)acetamide |
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1. Yunyun X, et al. Front Chem. 2025 Aug 11;13:1651402.

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