Catalog No.: PC-72669Not For Human Use, Lab Use Only.
Compound 4210 (MyD88 inhibitor 4210) is a small molecule inhibitor of MyD88, inhibits LPS-induced MyD88-mediated NF-kB-dependent expression of reporter activity with IC50 of 10-30 uM.
Compound 4210 (MyD88 inhibitor 4210) is a small molecule inhibitor of MyD88, inhibits LPS-induced MyD88-mediated NF-kB-dependent expression of reporter activity with IC50 of 10-30 uM.
Compound 4210 4210 inhibited MyD88 dimer formation which is critical for pro-inflammatory signaling.
Compound 4210 inhibited inflammatory cytokine production in human primary cells and increased therapeutic efficacy in mice with exposure to toxins of both grampositive and gram-negative pathogens.
Compound 4210 exhibits broad spectrum antiviral activity by up regulation of type I interferon.
