Compound 7004 | Probechem Biochemicals

Chemical Structure : Compound 7004

Compound 7004 (IRAK2 mimetic 7004)

Catalog No.: PC-35135Not For Human Use, Lab Use Only.

Compound 7004 (IRAK2 mimetic 7004) is a small molecule mimetic of a-helical domain of IRAK2, inhibit IL-33–induced NF-κB transcriptional activity (IC50=9.7 uM) by disrupting Myddosome formation.

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Biological Activity

Compound 7004 (IRAK2 mimetic 7004) is a small molecule mimetic of a-helical domain of IRAK2, inhibit IL-33-induced NF-κB transcriptional activity (IC50=9.7 uM) by disrupting Myddosome formation.
Compound 7004 decreases the IRAK2-IRAK4 association, attenuates IL-33-induced and OVA-induced asthma mouse models in vivo.
Compound 7004 attenuates the proinflammatory effects in asthma-like models.

Physicochemical Properties

M.Wt
Formula
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES

References

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Compound 7004 (IRAK2 mimetic 7004)

Biological Activity

Physicochemical Properties

References

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