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Connexin 43 inhibitor Gap 26

Chemical Structure : Connexin 43 inhibitor Gap 26

CAS No.: 197250-15-0

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Connexin 43 inhibitor Gap 26 (Gap26)

Catalog No.: PC-25862Not For Human Use, Lab Use Only.

Connexin 43 inhibitor Gap 26 (Gap26) is a connexin mimetic peptide inhibitor of Connexin 43 (Cx43), inhibits Gap junctions (GJs), confers protection to intact heart against myocardial ischemia injury.

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5 mg $128 In stock
10 mg $198 In stock
25 mg $358 In stock
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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Connexin 43 inhibitor Gap 26 (Gap26) is a connexin mimetic peptide inhibitor of Connexin 43 (Cx43), inhibits Gap junctions (GJs), blocks the electrical connection between cells facilitated by GJs, confers protection to intact heart against myocardial ischemia injury.

Physicochemical Properties

M.Wt 1550.80
Formula C70H107N19O19S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Val-Cys-Tyr-Asp-Lys-Ser-Phe-Pro-Ile-Ser-His-Val-Arg

References

1. Mohammed D, et al. Cureus. 2024 Apr 26;16(4):e59053.

2. Hawat G, et al. Pflugers Arch. 2010 Aug;460(3):583-92.

3. Pearson RA, et al. J Neurosci. 2005 Nov 16;25(46):10803-14.

4. Braet K, et al. Cell Calcium 33: 37-48.

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