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Cortexolone 17 alpha-propionate

Chemical Structure : Cortexolone 17 alpha-propionate

CAS No.: 19608-29-8

Cortexolone 17 alpha-propionate (Cortexolone 17α-propionate, CB-03-01, Clascoterone)

Catalog No.: PC-43500Not For Human Use, Lab Use Only.

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cortexolone 17 alpha-propionate (CB-03-01, Clascoterone) is a topical and peripherally selective androgen antagonist, displays a strong local antiandrogenic activity in hamster's flank organ test, does not exhibit antiandrogenic activity after subcutaneous injection in vivo.

Physicochemical Properties

M.Wt 402.52
Formula C24H34O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Pregn-4-ene-3,20-dione, 21-hydroxy-17-(1-oxopropoxy)-

References

1. Celasco G, et al. Arzneimittelforschung. 2004;54(12):881-6.

2. Trifu V, et al. Br J Dermatol. 2011 Jul;165(1):177-83.

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