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Cridanimod

Chemical Structure : Cridanimod

CAS No.: 38609-97-1

Cridanimod (10-CMA, XBIO-101)

Catalog No.: PC-60186Not For Human Use, Lab Use Only.

Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

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Biological Activity

Cridanimod (10-CMA, XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
Cridanimod displays extraordinary activity in phosphorylating IRF3 in the murine system.
Cridanimod also increases progesterone receptor (PrR) expression in endometrial tissue.

Physicochemical Properties

M.Wt 253.25
Formula C15H11NO3
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(9-oxoacridin-10-yl)acetic acid

References

1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.

2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.

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