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Cridanimod sodium

Chemical Structure : Cridanimod sodium

CAS No.: 58880-43-6

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Cridanimod sodium (XBIO-101, XBIO101)

Catalog No.: PC-60187Not For Human Use, Lab Use Only.

Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    Cridanimod sodium (XBIO-101) is a potent type I interferon (IFN) inducer that directly binds to STING and triggers a strong antiviral response through the TBK1/IRF3 route.
    Cridanimod sodium (XBIO-101) displays extraordinary activity in phosphorylating IRF3 in the murine system.
    Cridanimod sodium (XBIO-101) also increases progesterone receptor (PrR) expression in endometrial tissue.

    Physicochemical Properties

    M.Wt 276.247
    Formula C15H11NNaO3
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO
    Chemical Name/SMILES

    2-(9-oxoacridin-10(9H)-yl)acetic acid, sodium salt

    References

    1. Cavlar T, et al. EMBO J. 2013 May 15;32(10):1440-50.

    2. Zhang H, et al. Sci Rep. 2015 Dec 16;5:18035.

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