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Croconazole

Chemical Structure : Croconazole

CAS No.: 77175-51-0

Croconazole

Catalog No.: PC-27953Not For Human Use, Lab Use Only.

Croconazole is an azole antifungal agent that shows inhibition of ergosterol biosynthesis, an essential component of fungal cell membranes, inhibits fungal enzyme sterol 14α-demethylase (CYP51). 

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Croconazole is an azole antifungal agent that shows inhibition of ergosterol biosynthesis, an essential component of fungal cell membranes, inhibits fungal enzyme sterol 14α-demethylase (CYP51). 

Physicochemical Properties

M.Wt 310.78
Formula C18H15ClN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(1-(2-((3-Chlorobenzyl)oxy)phenyl)vinyl)-1H-imidazole

References

1. Ogata M, et al. J Med Chem. 1983 May;26(5):768-70.

2. Scherr N, et al. Antimicrob Agents Chemother. 2012 Dec;56(12):6410-3.

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