Cusatuzumab
(Anti-human CD70 mAb, human IgG1-Lambda2; ARGX-110)
Catalog No.: PC-Ab1038Not For Human Use, Lab Use Only.
Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity activity, eliminated LSCs in vitro and in xenotransplantation experiments. Cusatuzumab triggers Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells..
Cusatuzumab (ARGX-110) is a human αCD70 monoclonal antibody with enhanced antibody-dependent cellular cytotoxicity activity, eliminated LSCs in vitro and in xenotransplantation experiments. Cusatuzumab triggers Fc-mediated cytotoxicity with enhanced ADCC and inhibition of CD70/CD27 signaling, resulting in killing of malignant cells such as leukemia blasts and stem cells.
Physicochemical Properties
M.Wt
Formula
Human IgG1-Lambda2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
PBS, pH 7.0
Contains no stabilizers or preservatives
