Chemical Structure : Cyclothiazide
CAS No.:
2259-96-3
Cyclothiazide
(Doburil)
Catalog No. : PC-61706Not For Human Use, Lab Use Only.
Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents.
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Purity & Documentation Purity:
>98% (HPLC) Select Batch: PC-6170601
Biological Activity
Cyclothiazide (Doburil) is a positive allosteric modulator of the AMPA and kainate receptors that potentiates AMPA-mediated glutamate currents。
Physicochemical Properties
M.Wt
389.88
Formula
C14H16ClN3O4S2
Appearance
Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
1,1-dioxide 3-bicyclo[2.2.1]hept-5-en-2-yl-6-chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide
References
1. Yamada KA, et al. J Neurosci
2. Deng L, et al. Proc Natl Acad Sci U S A
3. Qi J, et al. J Physiol
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