Cyclotriazadisulfonamide | Sec61 inhibitor

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Chemical Structure : Cyclotriazadisulfonamide

Cyclotriazadisulfonamide (CADA)

Catalog No.: PC-25108Not For Human Use, Lab Use Only.

Cyclotriazadisulfonamide (CADA) is a specific CD4-targeted HIV entry inhibitor, inhibits the co-translational translocation of human CD4 (huCD4) into the ER lumen in a signal peptide (SP)-dependent, also is a Sec61 translocon inhibitor.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

Physicochemical Properties

M.Wt	581.79
Formula	C31H39N3O4S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	9-Benzyl-3-methylene-1,5-ditosyl-1,5,9-triazacyclododecane

References

1. Victor Van Puyenbroeck, et al. Traffic. 2020 Feb;21(2):250-264.

2. Kurt Vermeire, et al. Curr HIV Res. 2008 May;6(3):246-56.

3. Pauwels E, et al. Int J Mol Sci. 2021 Nov 5;22(21):12007.

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Cyclotriazadisulfonamide (CADA)

Biological Activity

Physicochemical Properties

References

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