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Cynaroside

Chemical Structure : Cynaroside

CAS No.: 5373-11-5

Cynaroside (Luteolin 7-glucoside)

Catalog No.: PC-26867Not For Human Use, Lab Use Only.

Cynaroside (Luteolin 7-glucoside) is a flavonoid compound with anti-oxidative capabilities, is also a potent influenza RNA-dependent RNA polymerase (RdRp) inhibitor with IC50 of 32 nM, also inhibits H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases, also disrupts IGF2BP3-RTK interactions as an enhancer of tyrosine kinase inhibitor (TKI) efficacy.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cynaroside (Luteolin 7-glucoside) is a flavonoid compound with anti-oxidative capabilities, is also a potent influenza RNA-dependent RNA polymerase (RdRp) inhibitor with IC50 of 32 nM, also inhibits H2O2-induced apoptosis, has cytoprotection against oxidative stress-induced cardiovascular diseases, also disrupts IGF2BP3-RTK interactions as an enhancer of tyrosine kinase inhibitor (TKI) efficacy.

Physicochemical Properties

M.Wt 448.38
Formula C21H20O11
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(3,4-Dihydroxyphenyl)-5-hydroxy-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one

References

1. Wang ZW, et al. J Exp Clin Cancer Res. 2026 Mar 11;45(1):99.

2. Václav Zima, et al. Eur J Med Chem. 22 August 2020, 112754.

3. Xiao Sun, et al. J Cell Biochem. 2011 Aug;112(8):2019-29.

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