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Cyproheptadine

Chemical Structure : Cyproheptadine

CAS No.: 969-33-5

Cyproheptadine

Catalog No.: PC-26505Not For Human Use, Lab Use Only.

Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist and histamine H1 receptor (HRH1) inverse agonist, promotes FOXO3 nuclear translocation and increases FOXO target genes while suppressing inflammation.

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Biological Activity

Cyproheptadine hydrochloride is a potent and orally active 5-HT2A receptor antagonist and histamine H1 receptor (HRH1) inverse agonist, promotes FOXO3 nuclear translocation and increases FOXO target genes while suppressing inflammation.

Physicochemical Properties

M.Wt 323.86
Formula C21H22ClN
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

4-(5H-Dibenzo[a,d][7]annulen-5-ylidene)-1-methylpiperidine hydrochloride

References

1. Kurakazu I, et al. J Clin Invest. 2025 Aug 28;135(21):e183588.

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