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Cysteamine hydrochloride

Chemical Structure : Cysteamine hydrochloride

CAS No.: 156-57-0

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Cysteamine hydrochloride (2-Mercaptoethylamine hydrochloride)

Catalog No.: PC-45983Not For Human Use, Lab Use Only.

An agent for the treatment of nephropathic cystinosis and an antioxidant.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

An agent for the treatment of nephropathic cystinosis and an antioxidant; increases intracellular glutathione levels in cystinotic cells, also increases the rates of apoptosis in cystinotic cells; is an excellent scavenger of OH and HOCl and also reacts with H2O2; significantly increase the intracellular GSH levels; also causes autophagosome accumulation in cancer cells.

Other Indication

Approved

Physicochemical Properties

M.Wt 113.6096
Formula C2H8ClNS
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethanethiol, 2-amino-, hydrochloride (1:1)

References

1. Besouw, M, et al. Drug Discov Today, 2013. 18(15-16): p. 785-92.

2. de Matos, D.G, et al. Mol Reprod Dev, 1995. 42(4): p. 432-6.

3. Wan XM, et al. Int J Cancer. 2011 Sep 1;129(5):1087-95.

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