Chemical Structure : Cytochalasin A
CAS No.: 14110-64-6
Catalog No.: PC-28244Not For Human Use, Lab Use Only.
Cytochalasin A is a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, inhibits actin polymerization of brain tubulin and muscle actin, also inhibits HIV-1 protease with IC50 of 3 uM, inhibits growth and glucose transport in Saccharomyces.
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|---|---|---|---|
| 5 mg | $288 | In stock | |
| 10 mg | $498 | In stock | |
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Cytochalasin A is a cell-permeable fungal toxin and oxidized derivative of cytochalasin B, inhibits actin polymerization of brain tubulin and muscle actin, also inhibits HIV-1 protease with IC50 of 3 uM, inhibits growth and glucose transport in Saccharomyces.
| M.Wt | 477.59 | |
| Formula | C29H35NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3S,3aS,4S,6S,6aS,7E,10R,15Z,18aS)-3-benzyl-6-hydroxy-4,10-dimethyl-5-methylene-2,3,3a,4,5,6,6a,9,10,11,12,13-dodecahydro-1H-[1]oxacyclotetradecino[2,3-d]isoindole-1,14,17-trione |
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1. Manavathu EK, et al. Biochem Biophys Res Commun. 1976 Jul 12;71(1):280-5.
2. Himes RH, et al. Biochem Biophys Res Commun. 1976 Feb 23;68(4):1362-70.
3. Cunningham D, et al. J Bacteriol. 1979 Feb;137(2):925-32.
4. Jones LA, et al. Eukaryot Cell. 2010 Oct;9(10):1455-65.

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