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Chemical Structure : Cytochalasin B
CAS No.: 14930-96-2
Catalog No.: PC-62435Not For Human Use, Lab Use Only.
Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion, shows Kd value of 1.4-2.2 nM for F-actin.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $348 | In stock | |
| 10 mg | $548 | In stock | |
| 25 mg | Get quote | ||
| 100 mg | Get quote |
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Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion, shows Kd value of 1.4-2.2 nM for F-actin.
Cytochalasin B also inhibits glucose transport and platelet aggregation.
Cytochalasin B blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.
| M.Wt | 479.6 | |
| Formula | C29H37NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-[1]oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione |
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1. Theodoropoulos PA, et al. Biochem Pharmacol. 1994 May 18;47(10):1875-81.
2. Jung CY, et al. J Biol Chem. 1977 Aug 10;252(15):5456-63.
3. Tanaka Y, et al. Exp Cell Res. 1994 Jul;213(1):242-52.
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