Cytochalasin B |CAS:14930-96-2 Probechem Biochemicals

Chemical Structure : Cytochalasin B

CAS No.: 14930-96-2

Cytochalasin B

Catalog No.: PC-62435Not For Human Use, Lab Use Only.

Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion, shows Kd value of 1.4-2.2 nM for F-actin.

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Biological Activity

Cytochalasin B is a cell-permeable mycotoxin that inhibits network formation by actin filaments, inhibits cell movement and induces nuclear extrusion, shows Kd value of 1.4-2.2 nM for F-actin.
Cytochalasin B also inhibits glucose transport and platelet aggregation.
Cytochalasin B blocks adenosine-induced apoptotic body formation without affecting activation of endogenous ADP-ribosylation in leukemia HL-60 cells.

Physicochemical Properties

M.Wt	479.6
Formula	C29H37NO5
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	(3E,5R,9R,11E,12aS,13S,15S,15aS,16S,18aS)-16-Benzyl-5,13-dihydroxy-9,15-dimethyl-14-methylene-6,7,8,9,10,12a,13,14,15,15a,16,17-dodecahydro-2H-[1]oxacyclotetradecino[2,3-d]isoindole-2,18(5H)-dione

References

1. Theodoropoulos PA, et al. Biochem Pharmacol. 1994 May 18;47(10):1875-81.

2. Jung CY, et al. J Biol Chem. 1977 Aug 10;252(15):5456-63.

3. Tanaka Y, et al. Exp Cell Res. 1994 Jul;213(1):242-52.

Cytochalasin B

Biological Activity

Physicochemical Properties

References

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