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Cytosporone B

Chemical Structure : Cytosporone B

CAS No.: 321661-62-5

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Cytosporone B (Csn-B, Dothiorelone G)

Catalog No.: PC-23124Not For Human Use, Lab Use Only.

Cytosporone B (Csn-B, Dothiorelone G) is a specific naturally occurring nuclear orphan receptor Nur77/NR4A1 agonist with EC50 of 0.278 nM, targets the ligand binding domain of Nur77.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Cytosporone B (Csn-B, Dothiorelone G) is a specific naturally occurring nuclear orphan receptor Nur77 (NR4A1) agonist with EC50 of 0.278 nM, targets the ligand binding domain of Nur77.

Physicochemical Properties

M.Wt 322.40
Formula C18H26O5
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

Ethyl 2-(3,5-dihydroxy-2-octanoylphenyl)acetate

References

1. Zhan Y, et al. Cytosporone B is an agonist for nuclear orphan receptor Nur77. Nat Chem Biol. 2008 Sep;4(9):548-56.

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