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Chemical Structure : D-AP5
CAS No.: 79055-68-8
Catalog No.: PC-38029Not For Human Use, Lab Use Only.
D-AP5 is a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $198 | In stock | |
| 50 mg | $328 | In stock | |
| 100 mg | $548 | In stock | |
| 500 mg | Get quote |
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D-AP5 is a selective NMDA receptor antagonist that competes with glutamate binding and is commonly used to inhibit NMDA-dependent synaptic plasticity; D-AP5 reduces NMDA-induced depolarization of cortical neurons in vitro, Following spinal injection, D-AP5 results in rapid reduction of NMDA-response but no effect on spontaneously active neurons.
| M.Wt | 197.127 | |
| Formula | C5H12NO5P | |
| Appearance | Solid | |
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| Solubility |
10 mM in DMSO |
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1. Davies J, et al. Brain Res. 1986 Sep 10;382(1):169-73.
2. Javitt DC, et al. Neurosci Lett. 1987 Jul 22;78(2):193-8.
3. Manallack DT, et al. Neuroscience. 1989;30(1):87-94.
4. Coleman PA, et al. J Neurosci. 1988 Dec;8(12):4728-33.
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