D-IX216

Chemical Structure : D-IX216

Catalog No.: PC-25641Not For Human Use, Lab Use Only.

D-IX216 is a potent, selective Mycobacterial RNA polymerase (Mtb RNAP) with IC50 of 100 nM, slows MtbRNAP translocation in a sequence-independent manner.

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Biological Activity

D-IX216 is a potent, selective Mycobacterial RNA polymerase (Mtb RNAP) with IC50 of 100 nM, slows MtbRNAP translocation in a sequence-independent manner.

Physicochemical Properties

M.Wt	452.55
Formula	C24H25FN4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(1-((5-fluoro-2-(piperazin-1-yl)phenyl)amino)-1-oxo-3-phenylpropan-2-yl)thiophene-2-carboxamide

References

1. Herrera-Asmat O, et al. Elife. 2025 Oct 3;14:e105545.

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D-IX216

Biological Activity

Physicochemical Properties

References

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