Chemical Structure : D159153
Catalog No.: PC-35906Not For Human Use, Lab Use Only.
D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.
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D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.
M.Wt | 397.45 | |
Formula | C22H24FN3O3 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Wunder F, et al. Mol Pharm. 2013 Oct 7;10(10):3697-705.
2. Zhang C, et al. Neuropsychopharmacology. 2018 Oct;43(11):2299-2309.
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