D159153 |CAS 2734371-28-7 Probechem Biochemicals

Chemical Structure : D159153

Catalog No.: PC-35906Not For Human Use, Lab Use Only.

D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.

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Biological Activity

D159153 (D-159153) is a novel potent, allosteric inhibitor of PDE4 with cellular IC50 of 28.5 and 6.6 nM for PDE4B1 and PDE4D3, respectively.

M.Wt	397.45
Formula	C22H24FN3O3
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-(4-ethyl-2-fluoro-3-((2E,4E)-5-nitrohexa-2,4-dien-3-yl)benzyl)phenyl)urea

1. Wunder F, et al. Mol Pharm. 2013 Oct 7;10(10):3697-705.

2. Zhang C, et al. Neuropsychopharmacology. 2018 Oct;43(11):2299-2309.