D159687 | PDE4D inhibitor | Probechem Biochemicals

Chemical Structure : D159687

CAS No.: 1155877-97-6

D159687 (D 159687)

Catalog No.: PC-21518Not For Human Use, Lab Use Only.

D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs.

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Biological Activity

D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs.

Physicochemical Properties

M.Wt	366.85
Formula	C21H19ClN2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	1-(4-((3'-Chloro-6-methoxy-[1,1'-biphenyl]-3-yl)methyl)phenyl)urea

References

1. Alex B Burgin, et al. Nat Biotechnol. 2010 Jan;28(1):63-70.

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D159687 (D 159687)

Biological Activity

Physicochemical Properties

References

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