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D159687

Chemical Structure : D159687

CAS No.: 1155877-97-6

D159687 (D 159687)

Catalog No.: PC-21518Not For Human Use, Lab Use Only.

D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

D159687 is a selective, negative allosteric modulator (inhibitor) of PDE4D with IC50 of 1.9 nM, >1,000 time more selective against PDE4 compared with other PDEs.

Physicochemical Properties

M.Wt 366.85
Formula C21H19ClN2O2
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

1-(4-((3'-Chloro-6-methoxy-[1,1'-biphenyl]-3-yl)methyl)phenyl)urea

References

1. Alex B Burgin, et al. Nat Biotechnol. 2010 Jan;28(1):63-70.

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