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D609

Chemical Structure : D609

CAS No.: 83373-60-8

D609 (D-609)

Catalog No.: PC-45953Not For Human Use, Lab Use Only.

D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM.

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Biological Activity

D609 is a competitive inhibitor of PC-PLC with Ki of 6.4 uM.
D609 does not affect bacterial phosphatidylinositol-specific PLC, bovine pancreatic PLA2, or phospholipase D; has antioxidant, antiviral, and anti-tumor activities.
D609 also shows anti-inflammatory actions, blocking the induction of nitric oxide synthase by LPS in phagocytes (IC50=20 ug/ml).

Physicochemical Properties

M.Wt 266.4645
Formula C11H15KOS2
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

Carbonodithioic acid, O-(octahydro-4,7-methano-1H-inden-5-yl) ester, potassium salt (1:1)

References

1. Amtmann E. Drugs Exp Clin Res. 1996;22(6):287-94.

2. Adibhatla RM, et al. Neurochem Res. 2012 Apr;37(4):671-9.

3. Tschaikowsky K, et al. Br J Pharmacol. 1994 Nov;113(3):664-8.

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